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5-HTP, the intermediate metabolite between the amino acid L-tryptophan and serotonin, is extracted from the seed of an African plant (Griffonia simplicifolia). 5-HTP readily crosses the blood-brain barrier and increases central nervous system (CNS) synthesis of serotonin. Serotonin can affect sleep, appetite, temperature, sexual behaviour, and pain sensation. Through its effects on mood and cravings for food via seratonin, 5-HTP can help manage weight. This low-glycemic chewable form is safe for those controlling blood sugar.
Consult a health care practitioner: for use beyond 12 weeks or if symptoms persist or worsen, prior to use if you are pregnant or breastfeeding or taking carbidopa or drugs/supplements with serotonergic activity. These may include, but are not limited to, L-tryptophan, S-adenosylmethionine (SAMe), St. John's wort, antidepressants, pain killers, over the counter cough and cold medication containing dextromethorphan, anti-nausea medication and anti-migraine medication. Discontinue use and consult a health care practitioner if you show signs of weakness, oral ulcers, or abdominal pain accompanied by severe muscle pain or if you experience skin changes. Do not use if you have scleroderma. Exercise caution if operating heavy machinery, driving a motor vehicle or involved in activities requiring mental alertness. Some people may
experience, drowsiness, diarrhea, nausea, vomiting and abdominal pain.